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. 1975 Nov;12(5):943–946. doi: 10.1128/iai.12.5.943-946.1975

Effect of the antitumor antibiotic chromomycin A3 on the humoral immune response in rats.

R Nayak, K S Prasad, M Sirsi
PMCID: PMC415379  PMID: 1193731

Abstract

Chromomycin A3 (250 mug/kg) suppressed the humoral immune response in rats against sheep erythrocytes when administered 48 h or later after antigenic stimulus. The antibiotic at this dose enhanced immunity when given along with or before antigen administration. The natural heterohemagglutinin levels in rabbits and guinea pigs were not affected by the antibiotic (10 mug/kg per day x 7).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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