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. 1975 Nov;12(5):1224–1226. doi: 10.1128/iai.12.5.1224-1226.1975

Virus-induced diabetes mellitus. V. Biological differences between the M variant and other strains of encephalomyocarditis virus.

M E Ross, T Onodera, K Hayashi, A L Notkins
PMCID: PMC415422  PMID: 172456

Abstract

The M variant of encephalomyocarditis virus is very closely related serologically to five other strains of encephalomyocarditis virus. Despite the serological relationship, these five viruses differ markedly from the M variant in their tissue tropisms and only the M variant infects beta cells of the pancreas, producing diabetes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Boucher D. W., Hayashi K., Rosenthal J., Notkins A. L. Virus-induced diabetes mellitus. III. Influence of the sex and strain of the host. J Infect Dis. 1975 Apr;131(4):462–466. doi: 10.1093/infdis/131.4.462. [DOI] [PubMed] [Google Scholar]
  2. Boucher D. W., Notkins A. L. Virus-induced diabetes mellitus. I. Hyperglycemia and hypoinsulinemia in mice infected with encephalomyocarditis virus. J Exp Med. 1973 May 1;137(5):1226–1239. doi: 10.1084/jem.137.5.1226. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CRAIGHEAD J. E. SOME PROPERTIES OF THE ENCEPHALOMYOCARDITIS, COLUMBIA SK AND MENGO VIRUSES. Proc Soc Exp Biol Med. 1965 Jun;119:408–412. doi: 10.3181/00379727-119-30196. [DOI] [PubMed] [Google Scholar]
  4. Craighead J. E., Steinke J. Diabetes mellitus-like syndrome in mice infected with encephalomyocarditis virus. Am J Pathol. 1971 Apr;63(1):119–134. [PMC free article] [PubMed] [Google Scholar]
  5. Wellmann K. F., Volk B. W., Brancato P., Amsterdam D. Encephalomyocarditis virus (E variant) in mice. Pancreatic changes. Arch Pathol. 1973 May;95(5):304–311. [PubMed] [Google Scholar]

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