Table 1.
Haplotype settings and association scenarios for the simulation
| Haplotype | Frequency |
OR |
||||
|---|---|---|---|---|---|---|
| Setting | Hap | Pop1 | Pop 2 | RR | RC | C |
| HS1 | 01100 | 0.3 | 0.3 | 1 | 1 | 1 |
| 10100 | 0.005 | 0.005 | 3 | 3 | 1 | |
| 11011 | 0.01 | 0.01 | 2 | 1 | 1 | |
| 11100 | 0.155 | 0.155 | 1 | 1 | 1 | |
| 11111 | 0.11 | 0.42 | 1 | 2 | 2 | |
| 10011 | 0.42 | 0.11 | 1 | 1 | 1 | |
| HS2 | 01010 | 0.06 | 0.06 | 1 | 1 | 1 |
| 01100 | 0.25 | 0.25 | 1 | 1 | 1 | |
| 10000 | 0.08 | 0.005 | 1 | 2 | 2 | |
| 10100 | 0.005 | 0.08 | 3 | 3 | 1 | |
| 11011 | 0.01 | 0.01 | 2 | 1 | 1 | |
| 11100 | 0.09 | 0.09 | 1 | 1 | 1 | |
| 11101 | 0.085 | 0.085 | 1 | 1 | 1 | |
| 11111 | 0.1 | 0.1 | 1 | 1 | 1 | |
| 10011 | 0.32 | 0.32 | 1 | 1 | 1 | |
| HS3 | 00111 | 0.07 | 0.07 | 1 | 1 | 1 |
| 01000 | 0.02 | 0.02 | 1 | 1 | 1 | |
| 01011 | 0.05 | 0.05 | 1 | 1 | 1 | |
| 01101 | 0.06 | 0.06 | 1 | 1 | 1 | |
| 01110 | 0.14 | 0.14 | 1 | 1 | 1 | |
| 10010 | 0.08 | 0.005 | 1 | 2 | 2 | |
| 10100 | 0.005 | 0.08 | 3 | 3 | 1 | |
| 11011 | 0.01 | 0.01 | 2 | 1 | 1 | |
| 11101 | 0.09 | 0.09 | 1 | 1 | 1 | |
| 11110 | 0.13 | 0.13 | 1 | 1 | 1 | |
| 11111 | 0.1 | 0.1 | 1 | 1 | 1 | |
| 10001 | 0.245 | 0.245 | 1 | 1 | 1 | |