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. 1976 Dec;14(6):1290–1292. doi: 10.1128/iai.14.6.1290-1292.1976

Phage-dependent changes in Shigella flexneri type antigen synthesis.

I Financsek, I Ketyi, W Sasak, W Jankowski, E Janczura, T Chojnacki
PMCID: PMC415529  PMID: 793990

Abstract

Lysogenic conversion of Shigella flexneri type antigens was studied with the aid of wild-type and thermosensitive mutant phages. With all wild-type phages, the appearance of glycosylated antigen was accompanied by the appearance of polyprenyl phosphate glucose synthetase activity. With some of the mutant phages, the appearance of glycosylated antigen was not followed by the formation of lipid-linked glucose in the enzyme assay. The reverse has also been observed, i.e., the high rate of formation of lipid-linked glucose and the lack of V-type antigen.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Giammanco G. Conversion lysogénique de caractères antigéniques de Shigella flexneri (antigène II de type et complexe 7,8 de groupe) Ann Inst Pasteur (Paris) 1968 Jan;114(1):63–76. [PubMed] [Google Scholar]
  2. Jankowski W., Chojnacki T., Janczura E. Formation of polyisoprenol phosphate glucose in Shigella flexneri. J Bacteriol. 1972 Dec;112(3):1420–1421. doi: 10.1128/jb.112.3.1420-1421.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Jankowski W., Mańkowski T., Chojnacki T. Formation of polyprenol monophosphate glucose in Shigella flexneri. Biochim Biophys Acta. 1974 Jan 23;337(1):153–162. doi: 10.1016/0005-2760(74)90050-2. [DOI] [PubMed] [Google Scholar]
  4. Kétyi I., Vertényi A., Financsek I. A comparative study on Shigella flexneri converting phages. Acta Microbiol Acad Sci Hung. 1972;19(3):159–174. [PubMed] [Google Scholar]
  5. Lehnhardt W. F., Winzler R. J. Determination of neutral sugars in glycoproteins by gas-liquid chromatography. J Chromatogr. 1968 May 7;34(4):471–479. doi: 10.1016/0021-9673(68)80091-3. [DOI] [PubMed] [Google Scholar]
  6. Lindberg B., Lönngren J., Rudén U., Simmons D. A. A reinvestigation of Shigella flexneri O-antigens by methylation analysis. Eur J Biochem. 1973 Jan 3;32(1):15–18. doi: 10.1111/j.1432-1033.1973.tb02572.x. [DOI] [PubMed] [Google Scholar]
  7. MATSUI S. Antigenic changes in Shigella flexneri group by bacteriophage. Jpn J Microbiol. 1958 Apr;2(2):153–158. doi: 10.1111/j.1348-0421.1958.tb00066.x. [DOI] [PubMed] [Google Scholar]
  8. Simmons D. A. Immunochemistry of Shigella flexneri O-antigens: a study of structural and genetic aspects of the biosynthesis of cell-surface antigens. Bacteriol Rev. 1971 Jun;35(2):117–148. doi: 10.1128/br.35.2.117-148.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Tessman I. Mutagenic treatment of double- and single-stranded DNA phages T4 ans S13 with hydroxylamine. Virology. 1968 Jun;35(2):330–333. doi: 10.1016/0042-6822(68)90275-4. [DOI] [PubMed] [Google Scholar]
  10. Wright A. Mechanism of conversion of the salmonella O antigen by bacteriophageepsilon 34. J Bacteriol. 1971 Mar;105(3):927–936. doi: 10.1128/jb.105.3.927-936.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]

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