Skip to main content
PMC home page
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1995 Jun 20;92(13):5803–5807. doi: 10.1073/pnas.92.13.5803

Functional activation of the human ventrolateral frontal cortex during mnemonic retrieval of verbal information.

M Petrides 1, B Alivisatos 1, A C Evans 1
PMCID: PMC41589  PMID: 7597032

Abstract

Regional cerebral blood flow was measured with positron emission tomography during the performance of a verbal free recall task, a verbal paired associate task, and tasks that required the production of verbal responses either by speaking or writing. Examination of the differences in regional cerebral blood flow between these conditions demonstrated that the left ventrolateral frontal cortical area 45 is involved in the recall of verbal information from long-term memory, in addition to its contribution to speech. The act of writing activated a network of areas involving posterior parietal cortex and sensorimotor areas but not ventrolateral frontal cortex.

Full text

PDF
5803

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Auerbach S. H., Allard T., Naeser M., Alexander M. P., Albert M. L. Pure word deafness. Analysis of a case with bilateral lesions and a defect at the prephonemic level. Brain. 1982 Jun;105(Pt 2):271–300. doi: 10.1093/brain/105.2.271. [DOI] [PubMed] [Google Scholar]
  2. Buckner R. L., Petersen S. E., Ojemann J. G., Miezin F. M., Squire L. R., Raichle M. E. Functional anatomical studies of explicit and implicit memory retrieval tasks. J Neurosci. 1995 Jan;15(1 Pt 1):12–29. doi: 10.1523/JNEUROSCI.15-01-00012.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Evans A. C., Marrett S., Neelin P., Collins L., Worsley K., Dai W., Milot S., Meyer E., Bub D. Anatomical mapping of functional activation in stereotactic coordinate space. Neuroimage. 1992 Aug;1(1):43–53. doi: 10.1016/1053-8119(92)90006-9. [DOI] [PubMed] [Google Scholar]
  4. Evans A. C., Marrett S., Torrescorzo J., Ku S., Collins L. MRI-PET correlation in three dimensions using a volume-of-interest (VOI) atlas. J Cereb Blood Flow Metab. 1991 Mar;11(2):A69–A78. doi: 10.1038/jcbfm.1991.40. [DOI] [PubMed] [Google Scholar]
  5. Geschwind N. The organization of language and the brain. Science. 1970 Nov 27;170(3961):940–944. doi: 10.1126/science.170.3961.940. [DOI] [PubMed] [Google Scholar]
  6. Grasby P. M., Frith C. D., Friston K. J., Bench C., Frackowiak R. S., Dolan R. J. Functional mapping of brain areas implicated in auditory--verbal memory function. Brain. 1993 Feb;116(Pt 1):1–20. doi: 10.1093/brain/116.1.1. [DOI] [PubMed] [Google Scholar]
  7. Hier D. B., Mohr J. P. Incongruous oral and written naming. Evidence for a subdivision of the syndrome of Wernicke's aphasia. Brain Lang. 1977 Jan;4(1):115–126. doi: 10.1016/0093-934x(77)90010-4. [DOI] [PubMed] [Google Scholar]
  8. Howard D., Patterson K., Wise R., Brown W. D., Friston K., Weiller C., Frackowiak R. The cortical localization of the lexicons. Positron emission tomography evidence. Brain. 1992 Dec;115(Pt 6):1769–1782. doi: 10.1093/brain/115.6.1769. [DOI] [PubMed] [Google Scholar]
  9. Incisa della Rocchetta A., Milner B. Strategic search and retrieval inhibition: the role of the frontal lobes. Neuropsychologia. 1993 Jun;31(6):503–524. doi: 10.1016/0028-3932(93)90049-6. [DOI] [PubMed] [Google Scholar]
  10. Janowsky J. S., Shimamura A. P., Kritchevsky M., Squire L. R. Cognitive impairment following frontal lobe damage and its relevance to human amnesia. Behav Neurosci. 1989 Jun;103(3):548–560. doi: 10.1037//0735-7044.103.3.548. [DOI] [PubMed] [Google Scholar]
  11. Jetter W., Poser U., Freeman R. B., Jr, Markowitsch H. J. A verbal long term memory deficit in frontal lobe damaged patients. Cortex. 1986 Jun;22(2):229–242. doi: 10.1016/s0010-9452(86)80047-8. [DOI] [PubMed] [Google Scholar]
  12. Mohr J. P., Pessin M. S., Finkelstein S., Funkenstein H. H., Duncan G. W., Davis K. R. Broca aphasia: pathologic and clinical. Neurology. 1978 Apr;28(4):311–324. doi: 10.1212/wnl.28.4.311. [DOI] [PubMed] [Google Scholar]
  13. Paivio A., Yuille J. C., Madigan S. A. Concreteness, imagery, and meaningfulness values for 925 nouns. J Exp Psychol. 1968 Jan;76(1 Suppl):1–25. doi: 10.1037/h0025327. [DOI] [PubMed] [Google Scholar]
  14. Petrides M., Alivisatos B., Evans A. C., Meyer E. Dissociation of human mid-dorsolateral from posterior dorsolateral frontal cortex in memory processing. Proc Natl Acad Sci U S A. 1993 Feb 1;90(3):873–877. doi: 10.1073/pnas.90.3.873. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Petrides M., Alivisatos B., Meyer E., Evans A. C. Functional activation of the human frontal cortex during the performance of verbal working memory tasks. Proc Natl Acad Sci U S A. 1993 Feb 1;90(3):878–882. doi: 10.1073/pnas.90.3.878. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Petrides M. Impairments on nonspatial self-ordered and externally ordered working memory tasks after lesions of the mid-dorsal part of the lateral frontal cortex in the monkey. J Neurosci. 1995 Jan;15(1 Pt 1):359–375. doi: 10.1523/JNEUROSCI.15-01-00359.1995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Petrides M., Milner B. Deficits on subject-ordered tasks after frontal- and temporal-lobe lesions in man. Neuropsychologia. 1982;20(3):249–262. doi: 10.1016/0028-3932(82)90100-2. [DOI] [PubMed] [Google Scholar]
  18. Petrides M. Monitoring of selections of visual stimuli and the primate frontal cortex. Proc Biol Sci. 1991 Dec 23;246(1317):293–298. doi: 10.1098/rspb.1991.0157. [DOI] [PubMed] [Google Scholar]
  19. Petrides M., Pandya D. N. Association fiber pathways to the frontal cortex from the superior temporal region in the rhesus monkey. J Comp Neurol. 1988 Jul 1;273(1):52–66. doi: 10.1002/cne.902730106. [DOI] [PubMed] [Google Scholar]
  20. Raichle M. E., Fiez J. A., Videen T. O., MacLeod A. M., Pardo J. V., Fox P. T., Petersen S. E. Practice-related changes in human brain functional anatomy during nonmotor learning. Cereb Cortex. 1994 Jan-Feb;4(1):8–26. doi: 10.1093/cercor/4.1.8. [DOI] [PubMed] [Google Scholar]
  21. Raichle M. E., Martin W. R., Herscovitch P., Mintun M. A., Markham J. Brain blood flow measured with intravenous H2(15)O. II. Implementation and validation. J Nucl Med. 1983 Sep;24(9):790–798. [PubMed] [Google Scholar]
  22. Roeltgen D. P., Heilman K. M. Lexical agraphia. Further support for the two-system hypothesis of linguistic agraphia. Brain. 1984 Sep;107(Pt 3):811–827. doi: 10.1093/brain/107.3.811. [DOI] [PubMed] [Google Scholar]
  23. Roeltgen D. P., Sevush S., Heilman K. M. Phonological agraphia: writing by the lexical-semantic route. Neurology. 1983 Jun;33(6):755–765. doi: 10.1212/wnl.33.6.755. [DOI] [PubMed] [Google Scholar]
  24. Shallice T., Fletcher P., Frith C. D., Grasby P., Frackowiak R. S., Dolan R. J. Brain regions associated with acquisition and retrieval of verbal episodic memory. Nature. 1994 Apr 14;368(6472):633–635. doi: 10.1038/368633a0. [DOI] [PubMed] [Google Scholar]
  25. Tulving E., Kapur S., Markowitsch H. J., Craik F. I., Habib R., Houle S. Neuroanatomical correlates of retrieval in episodic memory: auditory sentence recognition. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2012–2015. doi: 10.1073/pnas.91.6.2012. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Wise R., Chollet F., Hadar U., Friston K., Hoffner E., Frackowiak R. Distribution of cortical neural networks involved in word comprehension and word retrieval. Brain. 1991 Aug;114(Pt 4):1803–1817. doi: 10.1093/brain/114.4.1803. [DOI] [PubMed] [Google Scholar]
  27. Worsley K. J., Evans A. C., Marrett S., Neelin P. A three-dimensional statistical analysis for CBF activation studies in human brain. J Cereb Blood Flow Metab. 1992 Nov;12(6):900–918. doi: 10.1038/jcbfm.1992.127. [DOI] [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES