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. 1970 Oct;2(4):387–391. doi: 10.1128/iai.2.4.387-391.1970

Role of Protein A in Nonspecific Immunofluorescence of Staphylococcus aureus

Arne Forsgren 1, Urban Forsum 1
PMCID: PMC416021  PMID: 16557850

Abstract

γG-globulin from nonimmunized rabbits and from rabbits immunized with various bacteria reacted in the immunofluorescence technique with protein A-containing Staphylococcus aureus. Pepsin digestion of most immunoglobulin preparations eliminated the reaction, thus showing that the Fc fragment is involved and that the reaction is not a true antigen-antibody reaction. As the specific immunological activity of the immunoglobulin molecules was intact after digestion, it is suggested that the method be used to eliminate reactions with S. aureus in the fluorescent-antibody technique.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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