Abstract
Gas chromatography of the serum of mice inoculated 6 hr earlier with Staphylococcus aureus, Escherichia coli K-12, and Clostridium chauvoei revealed the formation of products associated with the infections. Longer periods were required before compounds resulting from infecting the animals with Salmonella typhimurium and other Clostridium species were detected by gas chromatographic means. The technique is sensitive to the presence of metabolites elaborated in vivo as a result of the presence of 100 to 35,000 cells. Each bacterial species caused the formation of distinctive compounds in infected mice, and substances chromatographically identical to these products were generated by the microorganisms in vitro as well.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- COLEHOUR J. K., LEONARD R. H. SERUM FATTY ACIDS IN CORONARY ARTERY DISEASE. Clin Chim Acta. 1964 May;9:413–418. doi: 10.1016/0009-8981(64)90077-4. [DOI] [PubMed] [Google Scholar]
- Cawley L. P., Tretbar H. A., Musser B. O. Gas-liquid chromatographic studies of urinary 17-ketosteroids in three patients with adrenocorticotropin-producing bronchogenic carcinoma. Am J Clin Pathol. 1969 Jan;51(1):86–94. doi: 10.1093/ajcp/51.1.86. [DOI] [PubMed] [Google Scholar]
- Farshtchi D., Moss C. W. Characterization of bacteria by gas chromatography: comparison of trimethylsilyl derivatives of whole-cell hydrolysates. Appl Microbiol. 1969 Feb;17(2):262–267. doi: 10.1128/am.17.2.262-267.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Henis Y., Gould J. R., Alexander M. Detection and identification of bacteria by gas chromatography. Appl Microbiol. 1966 Jul;14(4):513–524. doi: 10.1128/am.14.4.513-524.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mitruka B. M., Alexander M. Rapid and sensitive detection of bacteria by gas chromatography. Appl Microbiol. 1968 Apr;16(4):636–640. doi: 10.1128/am.16.4.636-640.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mitruka B. M., Alexander M. Ultrasensitive detection of certain microbial metabolites by gas chromatography. Anal Biochem. 1967 Sep;20(3):548–550. doi: 10.1016/0003-2697(67)90300-4. [DOI] [PubMed] [Google Scholar]
- Mitruka B. M., Carmichael L. E., Alexander M. Gas chromatographic detection of in vitro and in vivo activities of certain canine viruses. J Infect Dis. 1969 Jun;119(6):625–634. doi: 10.1093/infdis/119.6.625. [DOI] [PubMed] [Google Scholar]
- Sprinkle T., Greer M., Williams C. M. Detection of argininosuccinic aciduria by gas chromatography. Clin Chim Acta. 1969 Jan;23(1):27–31. doi: 10.1016/0009-8981(69)90006-0. [DOI] [PubMed] [Google Scholar]
- Theiner M., Friedman L. Characterization of rat tissues by gas-liquid chromatography with the electron capture detector. Proc Soc Exp Biol Med. 1969 Jul;131(3):1073–1076. doi: 10.3181/00379727-131-34042. [DOI] [PubMed] [Google Scholar]
- YAMAKAWA T., UETA N. GASCHROMATOGRAPHIC STUDIES OF MICROBIAL COMPONENTS. I. CARBOHYDRATE AND FATTY ACID CONSTITUTION OF NEISSERIA. Jpn J Exp Med. 1964 Dec;34:361–374. [PubMed] [Google Scholar]
- Yoshioka, Kitamura M., Tamura Z. Rapid gas chromatographic analysis of microbial volatile metabolites. Jpn J Microbiol. 1969 Mar;13(1):87–93. doi: 10.1111/j.1348-0421.1969.tb00438.x. [DOI] [PubMed] [Google Scholar]