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. 1971 Feb;3(2):249–253. doi: 10.1128/iai.3.2.249-253.1971

Mouse Resistance Against Foot-and-Mouth Disease Virus Induced by Injections of Pyran

Jonathan Y Richmond a,1
PMCID: PMC416139  PMID: 16557961

Abstract

Mouse resistance to foot-and-mouth disease virus (FMDV) was induced by intraperitoneal injections of pyran copolymer. A biphasic pattern of protection occurred with greatest resistance 4 and 48 hr after injection of this polyanion. Viremia was not detectable in pretreated mice challenge-exposed with FMDV. Incubation of virus with pyran did not alter viral infectivity in mice or tissue culture. Serum interferon was demonstrated 1 and 2 days after pyran administration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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