Skip to main content
NCBI home page
Infection and Immunity logoLink to Infection and Immunity
. 1971 Feb;3(2):274–277. doi: 10.1128/iai.3.2.274-277.1971

Partial Reassociation Between the Deoxyribonucleic Acids of Neisseria lactamicus and Neisseria meningitidis1

E Weiss a, N N Wilson a, S Schramek a,2, J C Hill a
PMCID: PMC416143  PMID: 16557965

Abstract

The similarity in polynucleotide sequence of seven strains of Neisseria lactamicus to N. meningitidis and to each other was investigated. The per cent reassociation between single-stranded N. lactamicus deoxyribonucleic acid (DNA), immobilized on membrane filters, with labeled single-stranded DNA fragments derived from strain SD-6 (group C) of N. meningitidis varied from 75 to 56. With strain ATCC 23972 of N. lactamicus furnishing the labeled DNA fragments, reassociation was 72% with N. meningitidis, 31% with N. subflava, and 98 to 72% with the other strains of N. lactamicus. It is concluded that on the basis of DNA reassociation N. lactamicus can be distinguished from N. meningitidis and N. subflava, but constitutes a relatively heterogeneous species.

Full text

PDF
274

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cowie D. B., Szafranski P. Thermal chromatography of DNA-DNA reactions. Biophys J. 1967 Sep;7(5):567–584. doi: 10.1016/S0006-3495(67)86607-4. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Goldschneider I., Gotschlich E. C., Artenstein M. S. Human immunity to the meningococcus. II. Development of natural immunity. J Exp Med. 1969 Jun 1;129(6):1327–1348. doi: 10.1084/jem.129.6.1327. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Hollis D. G., Wiggins G. L., Weaver R. E. Neisseria lactamicus sp. n., a lactose-fermenting species resembling Neisseria meningitidis. Appl Microbiol. 1969 Jan;17(1):71–77. doi: 10.1128/am.17.1.71-77.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Kingsbury D. T. Deoxyribonucleic acid homologies among species of the genus Neisseria. J Bacteriol. 1967 Oct;94(4):870–874. doi: 10.1128/jb.94.4.870-874.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Kingsbury D. T., Fanning G. R., Johnson K. E., Brenner D. J. Thermal stability of interspecies Neisseria DNA duplexes. J Gen Microbiol. 1969 Feb;55(2):201–208. doi: 10.1099/00221287-55-2-201. [DOI] [PubMed] [Google Scholar]
  6. Kingsbury D. T., Weiss E. Lack of deoxyribonucleic acid homology between species of the genus Chlamydia. J Bacteriol. 1968 Oct;96(4):1421–1423. doi: 10.1128/jb.96.4.1421-1423.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. McConaughy B. L., Laird C. D., McCarthy B. J. Nucleic acid reassociation in formamide. Biochemistry. 1969 Aug;8(8):3289–3295. doi: 10.1021/bi00836a024. [DOI] [PubMed] [Google Scholar]
  8. SLATERUS K. W. Serological typing of meningococci by means of micro-precipitation. Antonie Van Leeuwenhoek. 1961;27:305–315. doi: 10.1007/BF02538460. [DOI] [PubMed] [Google Scholar]
  9. WATSON R. G., SCHERP H. W. The specific hapten of group C (group II alpha) meningococcus. I. Preparation and immunological behavior. J Immunol. 1958 Oct;81(4):331–336. [PubMed] [Google Scholar]
  10. Weiss E., Schramek S., Wilson N. N., Newman L. W. Deoxyribonucleic Acid Heterogeneity Between Human and Murine Strains of Chlamydia trachomatis. Infect Immun. 1970 Jul;2(1):24–28. doi: 10.1128/iai.2.1.24-28.1970. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Infection and Immunity are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES