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. 1971 Feb;3(2):304–307. doi: 10.1128/iai.3.2.304-307.1971

Effect of Antilymphocyte Serum on Reovirus Infection of Mice

Shiroh Ida 1, Yorio Hinuma 1
PMCID: PMC416147  PMID: 16557969

Abstract

Reovirus type 3 infection in mice was investigated, with particular reference to the effect of antilymphocyte serum. With virus inoculation, a characteristic acute disease was manifested in the mice younger than 5 days old but not in mice 7 days old or older. However, a single injection of antilymphocyte serum, which was prepared in rabbits immunized with mouse thymocytes, followed by virus inoculation induced the acute disease in mice 7 days old or older. The latter result suggests that this production of the acute disease may be due to a suppression of the cellular immune mechanism sensitive to antilymphocyte serum.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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