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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Hypertension. 2014 Jun 23;64(4):738–744. doi: 10.1161/HYPERTENSIONAHA.114.03811

Figure 1. PERK KO exacerbated TAC-induced cardiac hypertrophy and increase of lung weight in mice.

Figure 1

Diagram shows the approach for generation of PERKflox/flox-Cre mice (A); TAC operations were performed on wild type (WT) and PERK KO mice. Tissue was collected from WT and PERK KO mice 5 weeks after TAC. Summarized left ventricular weight, left atrial weight, lung weight, right ventricular weight and right atrial weight in WT and PERK KO mice (B-F). #p<0.05 compared to the corresponding wild type group.