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. 1971 Sep;4(3):307–314. doi: 10.1128/iai.4.3.307-314.1971

Intracellular Location of Treponema pallidum (Nichols Strain) in the Rabbit Testis

John A Sykes 1, James N Miller 2
PMCID: PMC416304  PMID: 4949494

Abstract

During investigations designed to obtain purified suspensions of virulent Treponema pallidum (Nichols strain), infected rabbit testicular tissue was routinely examined in the electron microscope. Morphologically typical T. pallidum were found intracellularly within the cytoplasmic substance of fibroblasts, interstitial and Leydig cells, and of spermatocytes. The importance of these observations to latency and treatment is discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Azar H. A., Pham T. D., Kurban A. K. An electron microscopic study of a syphilitic chancre. Engulfment of Treponema pallidum by plasma cells. Arch Pathol. 1970 Aug;90(2):143–150. [PubMed] [Google Scholar]
  2. Drusin L. M., Rouiller G. C., Chapman G. B. Electron microscopy of Treponema pallidum occurring in a human primary lesion. J Bacteriol. 1969 Feb;97(2):951–955. doi: 10.1128/jb.97.2.951-955.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Hasegawa T. Electron microscopic observations on the lesions of condyloma latum. Br J Dermatol. 1969 May;81(5):367–374. doi: 10.1111/j.1365-2133.1969.tb14000.x. [DOI] [PubMed] [Google Scholar]
  4. Jepsen O. B., Hougen K. H., Birch-Andersen A. Electron microscopy of treponema pallidum Nichols. Acta Pathol Microbiol Scand. 1968;74(2):241–258. doi: 10.1111/j.1699-0463.1968.tb03477.x. [DOI] [PubMed] [Google Scholar]
  5. Ovcinnikov N. M., Delektorskij V. V. Further studies of the morphology of Treponema pallidum under the electron microscope. Br J Vener Dis. 1969 Jun;45(2):87–116. doi: 10.1136/sti.45.2.87. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Willcox R. R., Guthe T. Treponema pallidum. A bibliographical review of the morphology, culture and survival of T. pallidum and associated organisms. Bull World Health Organ. 1966;35:1–169. [PMC free article] [PubMed] [Google Scholar]

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