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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Ophthalmology. 2013 Oct 15;120(12):2706–2713. doi: 10.1016/j.ophtha.2013.07.051

Table 2. Multivariate Logistic Regression for Evaluation of Risk Factors for Severe Retinopathy of Prematurity.

Model 1 (90 Days) All 684
Eyes with 76 Eyes
Developing SROP
Model 2 (105 Days) 468 ROP
Eyes with 76 Eyes
Developing SROP
Model 3 (105 Days)
146 Prethreshold ROP
Eyes with 76 Eyes Developing SROP



Beta Odds Ratio (95% CI) P Value Beta Odds Ratio (95% CI) P Value Beta Odds Ratio (95% CI) P Value
BW (each 100 g increase) −0.475 0.62 (0.42–0.93) 0.021 −0.416 0.66 (0.44–0.98) 0.039 −0.136 0.87 (0.58–1.32) 0.52
GA (wks) − 0.643 0.53 (0.37–0.74) <0.0005 −0.566 0.57 (0.40–0.81) 0.002 −0.317 0.73 (0.52–1.02) 0.067
Multiple birth (yes = 1, no = 0) 1.889 6.6 (2.3–19.3) 0.001 1.866 6.5 (2.2–18.9) 0.001 2.247 9.5 (2.4–36.7) 0.001
Race (black = 1, non-black = 0) −1.612 0.20 (0.075–0.53) 0.001 −1.533 0.22 (0.079–0.59) 0.003 −0.774 0.32 (0.099–2.14) 0.323
Gender (male = 1, female = 0) 0.569 1.8 (0.78–3.99) 0.171 0.546 1.7 (0.75–3.98) 0.199 1.230 3.4 (1.12–10.5) 0.031
Per capita income (each $10 000) −0.056 0.95 (0.90–0.999) 0.044 −0.057 0.94 (0.90–0.995) 0.033 −0.042 0.96 (0.89–1.03) 0.277
ADL (hours; cumulative 90 days after EDC) −0.334 0.72 (0.55–0.94) 0.015 −0. −0.
ADL (hours; cumulative 105 days after EDC) −0.363 0.70 (0.52–0.93) 0.013 −0.624 0.54 (0.37–0.78) 0.001

ADL = average day length; BW = birth weight; CI = confidence interval; EDC = estimated date of conception; GA = gestational age; ROP = retinopathy of prematurity; SROP = severe retinopathy of prematurity.