Table 1.
Clinical and Demographic Variables in Epilepsy and Control Groups
| Clinical variable | HS (n = 35) | non-HS (n = 7) | Necropsy (n = 8) | P |
|---|---|---|---|---|
| Age at collection | ||||
| Years ± SD | 36 ± 7 | 26 ± 13* | 49 ± 18* | 0.01 |
| Collected side | ||||
| Right/left | 18/17 | 4/3 | 4/4 | 0.84 |
| Gender | ||||
| Male/female | 17/18 | 2/5 | 3/5 | 0.45 |
| Duration of epilepsy | ||||
| Years ± SD | 25 ± 8* | 12 ± 9* | NA | <0.01 |
| Frequency of seizures | ||||
| #/month ± SD | 12 ± 9 | 36 ± 44 | NA | 0.16 |
| Seizure type | ||||
| CPS/CPS+GTCS | 10/25 | 3/4 | NA | 0.41 |
| HS side (based on MRI) | ||||
| Right/left/bilateral | 16/17/2 | NA | NA | – |
| IPI presence | ||||
| Yes/no | 21/14* | 1/6* | NA | 0.02 |
| FS in childhood | ||||
| yes/no/undetermined | 10/16/9 | 1/6/0 | NA | 0.38 |
SD, standard deviation; NA, not applicable; CPS, complex partial seizure; GTCS, generalized tonic-clonic seizure; HS, hippocampal sclerosis; MRI, magnetic resonance imaging; IPI, initial precipitant injury; FS, febrile seizure. Bold P-values indicate significant differences between groups, indicated by asterisks. P-values computed by using Student∼s t-test or Exact Fisher∼s test.