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. Author manuscript; available in PMC: 2014 Dec 19.
Published in final edited form as: Nature. 2014 May 4;510(7505):402–406. doi: 10.1038/nature13239

Extended Data Figure 4. Summary of karyotyping and Notch1 sequencing of shPten TALL tumors.

Extended Data Figure 4

a, Results from a multiplex FISH analysis of three different primary shPten induced T-ALL tumors. At least 10 cells were analyzed for each sample, and chromosomal gains, deletions or translocations are highlighted. b, Summary of Notch1 mutations identified in shPten and Pten KO tumors. c, Sequence of all shRNAs targeting murine Pten that were tested in the study. Sense and guide strand are highlighted in red.