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. 2014 Jul 8;5(14):5798–5807. doi: 10.18632/oncotarget.2185

Figure 4. PI3K/AKT participates in RBP2 induction by CagA through Sp1.

Figure 4

(A) and (B) RBP2 and Sp1 changes at RNA level and protein level with AKTi and CagA treatment solely or jointly in GC cells respectively. Data are mean±SD of 3 biological replicates, *: P <0.05 compared with control. (C) RBP2 promoter activity changes with AKTi treatment in SGC-7901 cells. Data are mean±SD of 3 biological replicates, *: P <0.05 compared with negative control. (D)Foci formation in GC cells with AKTi and CagA treatment solely or jointly. Representative images are shown here from three independent biological replicates.