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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Nature. 2014 Mar 23;509(7498):115–118. doi: 10.1038/nature13083

Extended Data Figure 7. Representative saturation curves of [3H]2MeSADP-specific binding to wild-type P2Y12R and various mutant receptors at a concentration range of 0.4–46 nM.

Extended Data Figure 7

The calculated Kd values from 3–6 independent experiments are listed in Extended Data Table 3. Non-specific binding was determined using 10 μM AZD1283.