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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Nanomedicine. 2014 May 14;10(7):1385–1388. doi: 10.1016/j.nano.2014.05.001

Figure 1.

Figure 1

3D TOF MR cholangiogram in a rat following intravenous injection of gadolinium-functionalized PFOB NP. (A) Baseline image showing no evidence of vasculature or common bile duct. (B) 1 min post-injection, the blood pool as seen in the heart, aorta (arrow), and peripheral vasculature have strong T1-weighted positive contrast from the NP that are still constrained within the vasculature. H=heart, L=liver. (C) Within 5 min, the NP are rapidly excreted through the common bile duct (arrows), reflecting the rapid shunt of contrast from the liver into the small intestine. (D). After 10 min the small intestine contains most of the contrast, that is passed on to the large intestines at 30 min (E) and 60 min (F).