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Injectable nanovesicle formulation made from the nanovesicle-embedded thermoresponsive matrix. (A) Schematic of in vivo studies of the glucose-responsive nanovesicle toward STZ-induced type 1 diabetic mice for regulation of the BG levels. (B) Nanovesicle integrated with thermoresponsive PF127 solution immediately formed a hydrogel at 37 °C (upper) in vitro and 3 min after subcutaneous injection (lower).
