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. 2014 Jul 7;5(16):6594–6602. doi: 10.18632/oncotarget.2175

Figure 3. Comparison of ploidy of chromosome 8 in CTCs before and after treatment.

Figure 3

(A) Images of CTCs with different ploidies of chromosome 8. (a) triploidy, (b) tetraploidy, (c) pentaploidy, and (d) > 5 copies. Nuclei of CTCs were stained with DAPI (blue) and the chromosome 8 was identified by centromere probe 8 SpectrumOrange probe (red dots). Scale bar = 5 μm. (B) Distributions of aneuploid CTCs in AGC patients before and after treatment. (C) Correlation of aneuploid CTCs to the therapeutic efficacy. Multiploidy of chromosome 8 contains pentaploidy and those > 5 copies.