Inhibition of basal and TNF-α–stimulated IL8 gene expression by bone morphogenetic proteins in isolated canine gastric epithelial cells. IL-8 mRNA abundance in (A) canine mucus and (B) parietal cells stimulated with TNF-α (10 ng/mL), in the presence and absence of BMP-2 (20 ng/mL), BMP-4 (20 ng/mL), and BMP-7 (20 ng/mL), alone or in combination, was measured by QRT-PCR and Northern blots, respectively. Values are shown as means ± standard error (n = 3). *P < .05 and #P < .05 vs basal and TNF-α-stimulated IL8 gene expression, respectively.