Table 3. Patient characteristics according to predicted risk of poor outcome (Definition #1).
| Predicted Risk* |
||||
|---|---|---|---|---|
| Low n=612 |
Intermediate n=1314 |
High n=211 |
P-Value | |
| Age (y) | 83.4 (8.2) | 85.0 (6.6) | 84.0 (7.0) | <0.001 |
| Male (%) | 43.0 | 53.3 | 78.2 | <0.001 |
| Coronary artery disease (%) | 77.6 | 78.4 | 79.1 | 0.878 |
| Cerebrovascular disease (%) | 25.3 | 27.1 | 27.5 | 0.685 |
| Carotid disease (%) | 30.1 | 25.8 | 25.1 | 0.119 |
| Peripheral vascular disease (%) | 42.5 | 42.8 | 37.9 | 0.410 |
| Diabetes mellitus (%) | 45.1 | 34.2 | 27.5 | <0.001 |
| Major arrhythmia (%) | 29.1 | 57.3 | 74.4 | <0.001 |
| Creatinine (mg/dL) | 1.17 (0.41) | 1.32 (0.46) | 1.60 (0.60) | <0.001 |
| Hemoglobin (g/dL) | 11.9 (1.5) | 11.7 (1.5) | 11.5 (1.6) | 0.018 |
| Mean arterial pressure (mmHg) | 86.6 (12.2) | 87.4 (13.2) | 86.9 (13.7) | 0.420 |
| Body mass index (kg/m2) | 28.0 (7.4) | 26.6 (5.9) | 25.6 (5.2) | <0.001 |
| Oxygen-dependent lung disease (%) | 2.5 | 9.5 | 44.5 | <0.001 |
| Pulmonary hypertension (%) | 35.8 | 41.6 | 42.2 | 0.043 |
| Mitral regurgitation (>1+) (%) | 20.9 | 26.6 | 30.3 | 0.006 |
| Aortic regurgitation (>1+) (%) | 9.2 | 11.5 | 8.5 | 0.181 |
| Mean aortic gradient (mmHg) (%) | 53.0 (15.2) | 41.3 (12.0) | 32.7 (9.7) | <0.001 |
| Ejection fraction (%) | 55.5 (11.2) | 51.2 (13.3) | 46.6 (15.0) | <0.001 |
| Stroke volume (mL/beat) | 68.9 (24.0) | 62.9 (19.4) | 61.1 (20.1) | <0.001 |
| Mini-Mental Status Exam score | 28.1 (2.1) | 27.3 (2.9) | 25.3 (4.3) | <0.001 |
| 6-Min Walk Test (% able to perform) | 89.2 | 61.2 | 19.0 | <0.001 |
| 6-Min Walk Test distance (m) | 208.9 (128.9) | 80.7 (88.6) | 13.2 (33.1) | <0.001 |
| KCCQ Overall Summary score | 50.2 (21.6) | 40.3 (20.8) | 29.4 (18.5) | <0.001 |
| SF-12 Mental Summary score | 49.6 (10.9) | 47.3 (11.2) | 43.9 (11.1) | <0.001 |
| STS mortality risk score | 10.7 (4.3) | 11.8 (4.3) | 12.6 (4.6) | <0.001 |
| Outcomes at 6 Months | ||||
| Dead (%) | 8.8 | 20.3 | 37.4 | <0.001 |
| Poor Outcome (%) | 17.8 | 36.5 | 55.0 | <0.001 |
KCCQ-OS, Kansas City Cardiomyopathy Questionnaire Overall Summary; STS, Society of Thoracic Surgeons
*
Low Risk: <25%, Intermediate Risk: 25 to <50%, High Risk: ≥50%