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Erythropoietin (rhEPO) treatment decreases apoptosis after liver ischemia-reperfusion (IR). A, B. Immunohistochemistry for activated caspase 3 in untreated liver after IR demonstrates immunoreactivity in non-parenchymal cells. B. rhEPO treatment prevents caspase activation after IR, as shown by immunohistochemistry. C. A fluorogenic caspase activity assay performed after IR shows that rhEPO decreases caspase activity in the ischemic liver. * = p<0.05 in treated vs. untreated samples
