Abstract
INTRODUCTION: Routine collection of data through hospital MDTs, and the recent amalgamation in a single national centre has allowed analysis of patient demographics and outcome nationally for patients with Gliablastoma Multiforme (GBM) for the first time. METHOD: A search strategy encompassing all patients coded with a GBM and treated between 2007 - 2011 was obtained from data linkage between Encore (National Cancer registration Service), HES (Hospital Episode Statistics), and RTDS (Radiotherapy Data Service, 2010 onwards). RESULTS: There were 10743 patients coded with GBM in this 5 year period, (6451 male, 4292 female) giving an overall national incidence of 4.1/100,000/year. Incidence increases with age, and is slowly increasing. Median survival was 5.6 months for women, 6.5 months for men and decreased significantly with increasing age. A diagnosis of GBM is more likely in the least deprived quintile. CONCLUSION: Patients with GBM have a poor prognosis. Men do better than women, and younger patients do better than the elderly. Lower incidences in deprived groups may relate to detection and reporting. The data presented can be used to examine individual regions, hospitals, surgeons, or oncologists, but care is required to ensure that this level of detail represents an accurate representation.