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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Immunotherapy. 2014;6(6):755–774. doi: 10.2217/imt.14.37

Figure 2. Design strategy for peptidomimetics.

Figure 2

(A) Epitope of a protein that has relevant biological function identified from functional studies. Peptidomimetic design based on (B) backbone modifications, (C) side-chain modifications using amino acid analogs and (D) secondary structures such as α-helix or β-turn mimetics [8,27–29]. (E) Examples of peptidomimetics that are therapeutically useful for cardiovascular disease [26].