Table 1. Efficiency of the following photo-Fenton decontamination of scrapie infected TiO₂ particles based on a bioassay employing C57BL/6J mice.

Group No	Description	Survival rate (%)	Clinically affected/ Total number	Survival interval ± standard error (days)
1	aPositive control, 1% brain homogenate	0	4/4	236.8 ± 2.3
2	aPositive control, contaminated rutile	0	5/5	249.8 ± 8.6
3	bphoto-Fenton, 180 min	67	2/6b	269.0 ± 32.0
4	photo-Fenton, 360 min	67	2/6	278.5 ± 22.5

Animals were inoculated with 0.02 g RML-contaminated TiO₂ particles following photo-Fenton treatment (56 μg mL⁻¹ Fe³⁺, 600 μg mL⁻¹ h⁻¹ H₂O₂, UV-A, pH: 3.5). Asymptomatic animals were sacrificed 453 d.p.i. Only clinically affected animals were taken into account in the calculation of the survival interval. ^aThe difference in the incubation period between the two positive control groups was not statistically significant, demonstrating similar initial infectivity titers. ^bAn asymptomatic individual was found with PK-resistant cerebral PrP, 453 d post inoculation (see Fig. S1).