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. 1976 Jan;13(1):140–145. doi: 10.1128/iai.13.1.140-145.1976

Inhibition of water absorption in the intestine by Staphylococcus aureus delta-toxin.

F A Kapral, A D O'Brien, P D Ruff, W J Drugan Jr
PMCID: PMC420588  PMID: 1248867

Abstract

Water absorption in intestinal segments was monitored by measuring the concentration of polyethylene glycol, a nonabsorbable reference marker, in a balanced salt solution continuously perfused through the lumen. Staphylococcus aureus delta-toxin inhibited water absorption in rabbit jejunum and ileum perfused in vivo and in guinea pig ileum perfused in vitro. Cholera toxin also interfered with water absorption in guinea pig ileum maintained in vitro, but S. aureus enterotoxin B had no demonstrable effect on this tissue.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DARLINGTON W. A., QUASTEL J. H. Absorption of sugars from isolated surviving intestine. Arch Biochem Biophys. 1953 Mar;43(1):194–207. doi: 10.1016/0003-9861(53)90099-x. [DOI] [PubMed] [Google Scholar]
  2. Huang K. C., Chen T. S., Rout W. R. Effect of staphylococcal enterotoxins A, B, and C, on ion transport and permeability across the flounder intestine. Proc Soc Exp Biol Med. 1974 Oct;147(1):250–254. doi: 10.3181/00379727-147-38320. [DOI] [PubMed] [Google Scholar]
  3. Kapral F. A. Inhibition of Staphylococcus aureus delta hemolysin by phospholipids. Proc Soc Exp Biol Med. 1972 Nov;141(2):519–521. doi: 10.3181/00379727-141-36812. [DOI] [PubMed] [Google Scholar]
  4. Kapral F. A., Miller M. M. Product of Staphylococcus aureus responsible for the scalded-skin syndrome. Infect Immun. 1971 Nov;4(5):541–545. doi: 10.1128/iai.4.5.541-545.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Kimbert D. V. Cyclic nucleotides and their role in gastrointestinal secretion. Gastroenterology. 1974 Nov;67(5):1023–1064. [PubMed] [Google Scholar]
  6. McGonagle T. J., Serebro H. A., Iber F. L., Bayless T. M., Hendrix T. R. Time of onset of action of cholera toxin in dog and rabbit. Gastroenterology. 1969 Jul;57(1):5–8. [PubMed] [Google Scholar]
  7. O'Brien A. D., Kapral F. A. Increased cyclic adenosine 3',5'-monophosphate content in guinea pig ileum after exposure to Staphylococcus aureus delta-toxin. Infect Immun. 1976 Jan;13(1):152–162. doi: 10.1128/iai.13.1.152-162.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Sullivan R., Asano T. Effects of staphylococcal enterotoxin B on intestinal transport in the rat. Am J Physiol. 1971 Jun;220(6):1793–1797. doi: 10.1152/ajplegacy.1971.220.6.1793. [DOI] [PubMed] [Google Scholar]

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