Abstract
Staphylococcus aureus isolates from humans and other animals were grown in biotin assay medium containing 12 mug of biotin per liter and compared to isolates from the same sources grown concurrently in medium containing adequate biotin. The two cultures were tested for production of coagulase, phosphatase, and fibrinolysin enzymes and for responses to various antimicrobial agents and bacteriophages. Organisms grown in biotin-deficient medium produced less phosphatase; coagulase and fibrinolytic activity was reduced, and they were more susceptible to antimicrobial agents than were normal organisms, but phage susceptibility was not greatly affected.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Hugo W. B., Davidson J. R. Effect of cell lipid depletion in Staphylococcus aureus upon its resistance to antimicrobial agents. 2. A ccomparison of the response of normal and lipid depleted cells of S. aureus to antibacterial drugs. Microbios. 1973 Jun-Aug;8(29):63–72. [PubMed] [Google Scholar]
- Meyer W. Uber die Brauchbarkeit des Kristallviolett-Testes zur Differenzierung von Staphylococcus aureus-Stämmen. Z Med Mikrobiol Immunol. 1967;153(2):158–168. [PubMed] [Google Scholar]