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. 1976 Mar;13(3):776–781. doi: 10.1128/iai.13.3.776-781.1976

Adjuvant effect of cord factor, a mycobacterial lipid.

R Saito, A Tanaka, K Sugiyama, I Azuma, Y Yamamura
PMCID: PMC420677  PMID: 818016

Abstract

Cord factor was a good adjuvant in mice and rats but exerted little if any adjuvant effect in guinea pigs. In rats, cord factor not only enhanced antibody production but also induced delayed hypersensitivity. Wax D was a weak adjuvant in mice. Cord factor caused a marked inflammatory swelling at the sites of injection in mice, but it caused no such swelling in rats and guinea pigs.

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Selected References

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