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. 1976 Jun;13(6):1601–1605. doi: 10.1128/iai.13.6.1601-1605.1976

Effect of enterobacterial common antigen on mouse virulence of Salmonella typhimurium.

M V Valtonen, U M Larinkari, M Plosila, V V Valtonen, P H Mäkelä
PMCID: PMC420807  PMID: 786878

Abstract

A series of nearly isogenic O4-12, and O-6,7 Salmonella typhimurium strains differing in regard to the enterobacterial common antigen (ECA) were constructed by conjugation. When tested in intraperitoneal infection of mice, the O-4,12 strains containing ECA were more virulent than their O-4,12 sister recombinants without ECA (P = less than 0.001). The same difference could be shown with ECA-positive and ECA-negative S. typhimurium derivatives, whose O antigens were of the group C type (O-6,7). The ECA-positive and ECA-negative O-4,12 strains did not differ in their growth rates in broth or clearance rates in vivo.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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