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. 1977 Jul;17(1):21–27. doi: 10.1128/iai.17.1.21-27.1977

Common (non-type-specific) antigens of group A streptococci.

I M Lyampert, S G Shuratova, V V Akimova, V P Bukhova, V Y Kolesnikova
PMCID: PMC421076  PMID: 407162

Abstract

Two common (non-type-specific) antigens in HCl extracts prepared from group A streptococcal cultures of different types were analyzed by immunodiffusion methods. These antigens are sensitive to trypsin and are apparently related to the cell wall proteins. The common antigens tested belong to a category of nonprotective non-type-specific antigens. The presence of common antigens in the HCl extracts should be taken into consideration when M-proteins are determined. The detection of one of the common antigens may be used as a virulence index, since this antigen is characteristic of the group A streptococcal cultures with enhanced virulence.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BECKER C. G. SELECTION OF GROUP A STREPTOCOCCI RICH IN M-PROTEIN FROM POPULATIONS POOR IN M-PROTEIN. Am J Pathol. 1964 Jan;44:51–60. [PMC free article] [PubMed] [Google Scholar]
  2. Beachey E. H., Alberti H., Stollerman G. H. Delayed hypersensitivity to purified streptococcal m protein in guinea pigs and in man. J Immunol. 1969 Jan;102(1):42–52. [PubMed] [Google Scholar]
  3. Beachey E. H., Stollerman G. H. Mediation of cytotoxic effects of streptococcal M protein by nontype-specific antibody in human sera. J Clin Invest. 1973 Oct;52(10):2563–2570. doi: 10.1172/JCI107448. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Fox E. N., Wittner M. K., Dorfman A. Antigenicity of the M proteins of group A hemolytic streptococci. 3. Antibody responses and cutaneous hypersensitivity in humans. J Exp Med. 1966 Dec 1;124(6):1135–1151. doi: 10.1084/jem.124.6.1135. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Goudie R. B., Horne C. H., Wilkinson P. C. A simple method for producing antibody specific to a single selected diffusible antigen. Lancet. 1966 Dec 3;2(7475):1224–1226. doi: 10.1016/s0140-6736(66)92305-1. [DOI] [PubMed] [Google Scholar]
  6. Jackson R. W., Moskowitz M. Nature of a red cell sensitizing substance from streptococci. J Bacteriol. 1966 Jun;91(6):2205–2209. doi: 10.1128/jb.91.6.2205-2209.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. LANCEFIELD R. C. Differentiation of group A streptococci with a common R antigen into three serological types, with special reference to the bactericidal test. J Exp Med. 1957 Oct 1;106(4):525–544. doi: 10.1084/jem.106.4.525. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  9. Lyampert I. M., Danilova T. A. Immunological phenomena associated with cross-reactive antigens of micro-organisms and mammalian tissues. Prog Allergy. 1975;18:423–477. [PubMed] [Google Scholar]
  10. Lyampert I. M., Smirnova M. N., Semina N. A. Delayed-type hypersensitivity and the formation of antibodies in animals sensitized with group a streptococcus antigens. J Hyg Epidemiol Microbiol Immunol. 1967;11(2):160–170. [PubMed] [Google Scholar]
  11. MAXTED W. R. The indirect bactericidal test as a means of identifying antibody to the M antigen of Streptococcus pyogenes. Br J Exp Pathol. 1956 Aug;37(4):415–422. [PMC free article] [PubMed] [Google Scholar]
  12. Myoda T. T., Wiley G. G., Bruno P. N. Cross-reactions among group A streptococci. IV. Extraction, separation and purification of two protective antigens of type G 1 cocci. J Immunol. 1973 Jul;111(1):249–259. [PubMed] [Google Scholar]
  13. Osterland C. K., Miller E. J., Karakawa W. W., Krause R. M. Characteristics of streptococcal group-specific antibody isolated from hyperimmune rabbits. J Exp Med. 1966 Apr 1;123(4):599–614. doi: 10.1084/jem.123.4.599. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Vosti K. L. Characterization of a non-type-specific antigen(s) associated with group A streptococcal type 12 M protein. Infect Immun. 1975 Jun;11(6):1300–1306. doi: 10.1128/iai.11.6.1300-1305.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Vvedenskaia O. I., Liampert I. M., Shved I. V. Perekrestnye reaktsii v bakteritsidnom teste pri izuchenii kul'tur streptodokka gruppy A raznykh tipov. Zh Mikrobiol Epidemiol Immunobiol. 1972 Apr;49(4):97–100. [PubMed] [Google Scholar]
  16. WEIL-MALHERBE H., GREEN R. H. The catalytic effect of molybdate on the hydrolysis of organic phosphate bonds. Biochem J. 1951 Aug;49(3):286–292. [PMC free article] [PubMed] [Google Scholar]
  17. WILSON A. T., WILEY G. G. THE CELLULAR ANTIGENS OF GROUP A STREPTOCOCCI; IMMUNOELECTROPHORETIC STUDIES OF THE C, M, T, PGP, E4, F, AND E ANTIGENS OF SEROTYPE 17 STREPTOCOCCI. J Exp Med. 1963 Oct 1;118:527–556. doi: 10.1084/jem.118.4.527. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Widdowson J. P., Maxted W. R., Pinney A. M. An M-associated protein antigen (MAP) of group A streptococci. J Hyg (Lond) 1971 Dec;69(4):553–564. doi: 10.1017/s0022172400021823. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Wiley G. G., Bruno P. N. Cross-reactions among Group A streptococci. I. Precipitin and bactericidal cross-reactions among types 33, 41, 43, 52, and Ross. J Exp Med. 1968 Nov 1;128(5):959–968. doi: 10.1084/jem.128.5.959. [DOI] [PMC free article] [PubMed] [Google Scholar]

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