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. 1977 Aug;17(2):319–324. doi: 10.1128/iai.17.2.319-324.1977

Mechanisms of resistance to Corynebacterium kutscheri in mice.

R G Hirst, R Campbell
PMCID: PMC421121  PMID: 892907

Abstract

Involvement of the mononuclear phagocyte system in the mechanism of resistance to Corynebacterium kutscheri was studied in C57B1/6 and Swiss Lynch mice. A major difference between the two mouse strains was that the phagocytic cells of the livers of C57B1/6 mice destroyed the bacteria with much greater efficiency. There was no evidence of serum factors which might have led to this greater bacterial killing observed in the C57B1/6 mice, and in vivo phagocytosis of C. kutscheri was identical in both mouse strains. Resistance to C. kutscheri could be transferred with spleen and/or bone marrow cells from resistant (Swiss Lynch X C57B1/6) F1 mice to 650-rad irradiated susceptible Swiss Lynch mice. Nonspecific and acquired mechanisms of resistance to C. kutscheri are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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