Table 1.
Basic Patient and Tumor Characteristics.
| Variable | n (%) | |
|---|---|---|
| N | 140 | |
| Age, years | Mean ± SD | 53.7 ± 13.5 |
| Median (range) | 51 (25.5-86.1) | |
| Menopausal status | Premenopausal | 65 (46.4) |
| Postmenopausal | 75 (53.6) | |
| Tumor stage | II | 50 (35.7) |
| III | 90 (64.3) | |
| Tumor status | T2 | 39 (27.9) |
| T3 | 42 (30.0) | |
| T4 | 59 (42.1) | |
| Node status | N0 | 47 (33.6) |
| N1 | 63 (45.0) | |
| N2 | 26 (18.6) | |
| N3 | 4 (2.9) | |
| Tumor grade | 1 | 11 (7.9) |
| 2 | 63 (45.0) | |
| 3 | 66 (47.1) | |
| ER | Positive | 87 (62.1) |
| Negative | 53 (37.9) | |
| PR | Positive | 68 (48.6) |
| Negative | 72 (51.4) | |
| Ki67 status | < 20% | 74 (42.9) |
| ≥ 20% | 60 (52.9) | |
| Missing data | 6 (4.3) | |
| HER2 | Normal | 113 (81) |
| Amplification | 24 (17) | |
| Missing data | 3 (2) | |
| TOP2A | Normal | 124 (89) |
| Amplification | 7 (5) | |
| Deletion | 6 (4) | |
| Missing data | 3 (2) | |
| Neoadjuvant therapy | FEC75/FAC60 | 55 (39.3) |
| EC-D | 85 (60.7) | |
| Surgical treatment | Mastectomy | 88 (62.9) |
| Lumpectomy | 52 (37.1) | |
| Pathologic response | Complete | 13 (9.3%) |
| Residual disease | 127 (90.7) |