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. 1977 Nov;18(2):454–458. doi: 10.1128/iai.18.2.454-458.1977

Mouse virulence of Salmonella typhimurium mutants deficient in two major outer membrane proteins.

M V Valtonen, M Nurminen, V Johansson, P H Makela
PMCID: PMC421254  PMID: 336546

Abstract

The role of several outer membrane components as virulence factors is well established. We have now isolated spontaneous mutants and conjugational hybrids of smooth mouse virulent Salmonella typhimurium deficient in two major outer-membrane proteins. The lack of the 34,000- and/or 36,000-dalton proteins was confirmed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Mutants and recombinants were then tested for their mouse virulence by intraperitoneal inoculation and were found to be as virulent as the parent strain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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