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. 1977 Dec;18(3):828–832. doi: 10.1128/iai.18.3.828-832.1977

Experimental Rat model for Corynebacterium renale-induced pyelonephritis.

R J Jerusik, S Kadis, W L Chapman Jr, R E Wooley
PMCID: PMC421308  PMID: 591068

Abstract

The laboratory rat was able to serve as a model for ascending pyelonephritis after implantation of a zinc disk coated with Corynebacterium renale into the urinary bladder because it satisfied three different criteria for infection. The production of an alkaline urine and the presence of significant numbers of C. renale in the kidneys, as well as distinct pyelonephritic lesions as revealed by histological examination, were observed in all rats infected with C. renale. Control rats that harbored sterile disks in their urinary bladders exhibited none of the above effects.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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