Table 2.
Radiographic and clinical outcomes
| Variable | All | No SS | SS on first pass CTA | SS on delayed CTA | SS on either CTA acquisition |
|---|---|---|---|---|---|
| Primary outcome – hematoma expansion | |||||
| Number of subjects (%) | 74(100.0) | 59(79.7) | 10(13.5) | 14(18.9) | 15(20.3) |
| Baseline ICH volume (median, IQR) | 24.3(5.8-53.5) | 19.1(5.0-40.9) | 32.9(22.3-64.7) | 62.5(27.4-88.6) | 54.6(28.5-86.5) |
| Follow-up ICH volume (median, IQR) | 23.1(5.7-55.9) | 20.2(5.2-39.5) | 54.7(27.1-113.7) | 79.3(27.1-112.8) | 75.6(30.7-108.4) |
| Intraventricular extension | 31(41.9) | 23(39.0) | 5(50.0) | 7(50.0) | 8(53.3) |
| Time to follow-up CT in hours (median, IQR) | 6.4(4.8-10.5) | 6.4(4.9-11.5) | 4.7(4.0-7.2) | 6.0(4.1-8.0) | 6.3(4.1-8.7) |
| Hematoma expansion >6 mL or 33% | 11(14.9) | 4(6.8) | 6(60.0) | 6(42.9) | 7(46.7) |
| Absolute change in volume in mL (median, IQR) | 0.05(−1.8 to 1.4) | −0.1(−1.8 to 0.7) | 12.1(1.0 to 30.2) | 2.9(−3.4 to 20.0) | 4.2(−3.4 to 20.3) |
| Absolute change in volume in % (median, IQR) | 0.8(−8.2 to 7.7) | −2.2(−9.2 to 5.0) | 49.4(2.8 to 82.6) | 5.1(−4.1 to 74.2) | 5.8(−4.1 to 71.4) |
| Secondary outcome – in-hospital mortality | |||||
| Number of subjects | 121(100.0) | 85(70.2) | 21(17.4) | 35(28.9) | 36(29.8) |
| In-hospital mortality | 48(39.7) | 22(25.9) | 15(71.4) | 26(74.3) | 26(72.2) |
| Secondary outcome – poor outcome at discharge | |||||
| Number of subjects | 117(100.0) | 83(70.9) | 21(17.9) | 33(28.2) | 34(29.1) |
| mRS at discharge (median, range) | 4(1-6) | 4(1-6) | 6(1-6) | 6(1-6) | 6(1-6) |
| Poor outcome (mRS≥3) | 99(84.6) | 66(79.5) | 20(95.2) | 32(97.0) | 33(97.1) |
SS = Spot Sign; CTA = Computed Tomography Angiography; ICH = Intracerebral Hemorrhage; IQR = Interquartile Range; mL = milliliter; mRS = Modified Rankin Scale