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. 1977 Jan;15(1):287–294. doi: 10.1128/iai.15.1.287-294.1977

Humoral immunity in vaginal candidiasis.

S Mathur, G V Koistinen, E O Horger 3rd, T A Mahvi, H H Fudenberg
PMCID: PMC421360  PMID: 319061

Abstract

Serum antibody titers to Candida albicans were estimated in 37 women with recurrent vaginal candidiasis and in 148 normal American and Finnish subjects, using the passive-hemagglutination technique. The antibody titers ranged from 0 to 16 in normal individuals and 4 to 256 in vaginal candidiasis patients. Antibodies to C. albicans in the sera of vaginal candidiasis patients were found to be the secretory immunoglobulin A type, as determined by gel filtration and double-diffusion tests. The results were confirmed by the indir-ct fluorescent-antibody technique. Our findings suggest that, in vaginal candidiasis, the antibody response is mainly local, consisting of secretory immunoglobulin A, some of which finds its way into systemic circulation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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