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. 1977 Mar;15(3):772–775. doi: 10.1128/iai.15.3.772-775.1977

Reliable in vivo model for latent herpes simplex virus reactivation with peripheral virus shedding.

A B Nesburn, M T Green, M Radnoti, B Walker
PMCID: PMC421438  PMID: 192675

Abstract

A long-sought laboratory model, a reliable system for in vivo reactivization of latent herpes simplex infection with peripheral shedding of active virus, is present. Results demonstrate that surgical stimulation of latently infected rabbit trigeminal ganglia induces peripheral release of infectious herpes simplex virus. Virus could be cultured from the tear film in 83% of the stimulated animals' eyes within 48 h.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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