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. 1977 Mar;15(3):796–798. doi: 10.1128/iai.15.3.796-798.1977

Biological properties of Shigella flexneri 2A toxin and its serological relationship to Shigella dysenteriae 1 toxin.

A D O'Brien, M R Thompson, P Gemski, B P Doctor, S B Formal
PMCID: PMC421442  PMID: 323142

Abstract

A toxin extracted from heat-inactivated, alkaline-treated Shigella flexneri 2a showed biological properties similar to those of Shigella dysenteria 1 toxin. The S, flexneri 2a toxin was lethal to mice, enterotoxic for ileal loops of rabbits, and cytotoxic for HeLa cells. A serological relationship between S. flexneri 2a and S. dysenteriae 1 toxin was shown with cross neutralization tests.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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