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. 2014 Oct 28;2:e649. doi: 10.7717/peerj.649

Figure 2. Modulation of γ-secretase by DAPT.

Figure 2

Fitting of (A) the mechanistic equation (Eq. (10)), (B) Equation 10 refit and (C) the proposed empirical equation (Eq. (5)) to the raw data for DAPT and γ-secretase interactions. Each line represents a different concentrations of the amyloid precursor protein C-terminal fragment 99, expression vector (Svedruzic, Popovic & Sendula-Jengic, 2013).