Table 2. Characteristics of AML-M6a versus AML-M6b patients.
Characteristics | AML-M6a | AML-M6b | P |
---|---|---|---|
No. Patients | 78 | 30 | |
Sex: Male, no. (%) | 53 (68) | 17 (55) | 0.36 |
Median Age, Years (range) | 57 (17-76) | 61 (18-85) | 0.07 |
Prior AHD/MDS, no. (%) | 37 (47) | 17 (57) | 0.51 |
Prior Chemo or XRT, no. (%) | 14 (18) | 13 (43) | 0.01 |
Median WBC, ×109/L (range) | 2.1 (0.5-45.1) | 3.6 (0.3-21.8) | 0.07 |
Median Hb, g/dL (range) | 7.7 (2.5-12.6) | 7.7 (5.3-11.8) | 0.33 |
Median Platelets, × 109/L (range) | 45 (3-222) | 21 (3-119) | 0.01 |
Median β2 Microglobulin, mg/L (range) | 2.1 (1.2-8.1) | 3.2 (1.7-13.3) | 0.01 |
Median LDH, IU/L (range) | 677 (226-25,980) | 1087 (399-17,313) | 0.004 |
Cytogenetics*, no. (%) | |||
Poor | 50 (65) | 25 (86) | 0.03 |
Intermediate | 27 (35) | 4 (14) | |
BM Dysplasia**, no. (%) | 56 (80) | 14 (93) | 0.28 |
Protected Environment, no. (%) | 60 (77) | 16 (53) | 0.02 |
there were 77 available patients in M6a group and 29 in M6b
there were 71 available patients in M6a group and 14 in M6b