Table 9. Selected Reports of AML-M6.
| MDACC | Colita et al.55 | Olopade et al.11 | Atkinson et al.19 | |
|---|---|---|---|---|
| Time Period | 1981-2006 | 1976-1999 | 1969-1991 | 1977-1990 |
| Number | 108 | 54 | 26 | 15 |
| Median Age, years (range) | 60 (17-85) | 59 (19-84) | 66 (6-85) | 65 (16-85) |
| Male, no. (%) | 70 (65%) | 40 (74%) | 16 (62%) | 7 (47%) |
| AHD/MDS, no. (%) | 54 (50%) | NR | NR | 3 (20%) |
| Treatment-related, no. (%) | 27 (25%) | NR | NR | 4 (27%) |
| Median WBC, ×109/L (range) | 2.4 (0.3-45.1) | 3.24 (0.4-367) | 3.7 (0.8-10.6) | 2.9 (1.2-6.2) |
| Median Hb, g/dL (range) | 7.7 (2.5-12.6) | 8.5 (4.7-13.4) | 6.5 (1.0-10.1) | 7.2 (2.4-14.7) |
| Median Platelet count, ×109/L (range) | 38 (3-222) | 47 (6-334) | 48 (12-819) | 48 (3-259) |
| Median Erythroblasts, % (range) | 61 (31-95) | NR | 64 (40-84) | NR |
| Poor-risk Karyotype, no. (%) | 75 (69%) | 18 (33%) | 17 (65%) | 4/6 (66%) |
| CR Rate, % | 63 | 54 | 62 | 30 |
| OS, months (range) | 8.2 (0-292+) | 9 (NR) | 5.7 (0.5-73.5) | 3.2 (1-84+) |
NR – not reported