Table 1.
Characteristics of study participants
| Controls (n = 80) | AAA (n = 80) | PAD (n = 40) | CAD (n = 80) | |
|---|---|---|---|---|
| Age (years) | 72.7 ± 6.1 | 74.8 ± 8.1 | 72.1 ± 9.4 | 75.0 ± 8.6 |
| Males (%) | 66 (82.5) | 63 (78.8) | 32 (80.0) | 67 (83.8) |
| BMI (kg/m2) | 25.9 ± 3.5 | 27.1 ± 4.4 | 26.3 ± 4.1† | 28.5 ± 4.5* |
| History IHD (%) | 0 (0) | 35 (43.8)† | 12 (30.0)† | 80 (100) |
| Smoking (pack years) | 0 (0–12.3) | 26.0 (10.0-42.6)* | 23.8 (6.9-40.0)* | 16.3 (0–33.1)* |
| Diabetes (%) | 5 (6.3) | 9 (11.3) | 6 (15.0) | 17 (21.3)* |
| Hypertension (%) | 25 (31.3) | 48 (60.0)* | 26 (65.0)* | 64 (80.0)* |
| Dyslipidemia (%) | 25 (31.3) | 43 (53.8)* | 28 (70.0)* | 60 (75.0)* |
| hs-CRP, mg/L | 1.9 (1.1-4.7) | 1.9 (0.9-5.1)† | 2.2 (1.3-5.7) | 4.5 (2.3-4.9)* |
| HDL-C mmol/L | 1.22 (1.05-1.49) | 1.11 (0.93-1.31)* | 1.16 (0.96-1.53) | 1.14 (0.93-1.31) |
| Hsp27, ng/ml | 2.68 (1.78-4.42) | 1.82 (0.91-3.37)*† | 1.93 (1.01-3.05)*† | 1.23 (0.84-2.12)* |
Age and BMI are shown as mean ± SD; Hsp27 and smoking (pack years) are shown as median (IQR); The categorical data is presented as number (percentage). *p < 0.001 versus control group; †p < 0.001 versus CAD group.
Body mass index (BMI), Ischemic heart disease (IHD), plasma high sensitivity C-reactive protein (hs-CRP), High-density lipoprotein cholesterol (HDL-C), Heat shock protein-27 (Hsp27).