TABLE 2 ] .

Change in Primary Outcome Parameters Between Baseline and Follow-up

Outcome	Mean ± SE				Time Effect P Value	Group × Time Effect P Value	Mean Change (95% CI) From Baseline to
	Baseline	Post	1MFU	6MFU			Post	1MFU	6MFU
ACT					< .001	.157
CART	17.6 ± 0.5	19.2 ± 0.5	18.8 ± 0.5	19.6 ± 0.6			1.6 (0.6 to 2.6)	1.2 (−0.0 to 2.5)	2.1 (0.6 to 3.6)
SLOW	16.6 ± 0.5	19.1 ± 0.5	19.8 ± 0.6	19.5 ± 0.6			2.5 (1.5 to 3.5)	3.2 (1.9 to 4.5)	2.9 (1.3 to 4.4)
Differential change	…	…	…	…			−0.9 (−2.3 to 0.5)	−2.0 (−3.8 to −0.2)	−0.8 (−3.0 to 1.4)
P value	…	…	…	…			.217	.034	.466
Pco2					< .001	.049
CART	36.3 ± 0.5	39.2 ± 0.5	39.0 ± 0.5	39.0 ± 0.7			2.9 (2.0 to 3.9)	2.7 (1.6 to 3.8)	2.7 (1.3 to 4.0)
SLOW	35.6 ± 0.5	37.3 ± 0.6	36.5 ± 0.6	35.6 ± 0.7			1.7 (0.7 to 2.8)	0.9 (−0.2 to 2.1)	0.0 (−1.4 to 1.5)
Differential change	…	…	…	…			1.2 (−0.2 to 2.7)	1.8 (0.2 to 3.3)	2.7 (0.7 to 4.6)
P value	…	…	…	…			.094	.031	.009
Diurnal peak flow					.005	.169
CART	10.0 ± 0.8	8.7 ± 0.7	10.1 ± 0.8	9.2 ± 0.7			−1.3 (−2.5 to −0.1)	0.1 (−1.5 to 1.6)	−0.8 (−2.4 to 0.7)
SLOW	9.8 ± 0.8	7.9 ± 0.7	8.1 ± 0.8	9.1 ± 0.7			−1.9 (−3.1 to −0.6)	−1.7 (−3.3 to −0.1)	−0.7 (−2.3 to 0.9)
Differential change	…	…	…	…			0.6 (−1.2 to 2.3)	1.8 (−0.4 to 4.0)	−0.2 (−2.4 to 2.1)
P value	…	…	…	…			.535	.114	.891

Differential change was calculated as the difference from baseline in the CART condition (eg, 1MFU − baseline) minus the difference from baseline for the SLOW condition; higher numbers indicate greater increases in CART vs SLOW. 1MFU = 1-mo follow-up; 6MFU = 6-mo follow-up; ACT = Asthma Control Test. See Table 1 legend for expansion of other abbreviations.