TABLE 3 ] .
Change in Secondary Outcome Parameters Between Baseline and Follow-up
| Outcome | Mean ± SE | Time Effect P Value | Group × Time Effect P Value | Mean Change (95% CI) From Baseline to | |||||
| Baseline | Post | 1MFU | 6MFU | Post | 1MFU | 6MFU | |||
| ASQ | < .001 | .039 | |||||||
| CART | 2.4 ± 0.1 | 1.9 ± 0.1 | 1.9 ± 0.1 | 1.7 ± 0.1 | −0.4 (−0.6 to −0.2) | −0.4 (−0.7 to −0.2) | −0.7 (−0.9 to −0.4) | ||
| SLOW | 2.3 ± 0.1 | 1.8 ± 0.1 | 1.8 ± 0.1 | 2.0 ± 0.1 | −0.5 (−0.7 to −0.3) | −0.5 (−0.7 to −0.2) | −0.3 (−0.5 to −0.0) | ||
| Differential change | … | … | … | … | 0.1 (−0.2 to 0.4) | 0.0 (−0.3 to 0.4) | −0.4 (−0.7 to −0.0) | ||
| P value | … | … | … | … | .491 | .836 | .026 | ||
| ASC | < .001 | .042 | |||||||
| CART | 52.5 ± 1.3 | 49.2 ± 1.3 | 50.0 ± 1.4 | 46.5 ± 1.3 | −3.2 (−5.8 to −0.6) | −2.5 (−5.3 to 0.2) | −6.0 (−8.4 to −3.6) | ||
| SLOW | 52.4 ± 1.3 | 50.2 ± 1.3 | 48.7 ± 1.4 | 49.8 ± 1.3 | −2.2 (−4.8 to 0.4) | −3.7 (−6.5 to −0.9) | −2.5 (−4.9 to −0.1) | ||
| Differential change | … | … | … | … | −1.1 (−4.7 to 2.6) | 1.2 (−2.7 to 5.1) | −3.5 (−6.9 to −0.1) | ||
| P value | … | … | … | … | .565 | .545 | .044 | ||
| SF-12 physical | < .001 | .260 | |||||||
| CART | 49.7 ± 1.1 | 51.4 ± 1.0 | 51.0 ± 1.0 | 51.2 ± 0.9 | 1.7 (−0.1 to 3.5) | 1.3 (−1.0 to 3.5) | 1.5 (−0.8 to 3.7) | ||
| SLOW | 47.7 ± 1.2 | 51.5 ± 1.0 | 51.0 ± 1.1 | 52.2 ± 1.0 | 3.8 (1.9 to 5.8) | 3.3 (1.0 to 5.7) | 4.5 (2.1 to 6.8) | ||
| Differential change | … | … | … | … | −2.1 (−0.8 to 0.5) | −2.0 (−5.3 to 1.2) | −3.0 (−6.2 to 0.2) | ||
| P value | … | … | … | … | .116 | .214 | .067 | ||
| SF-12 mental | .244 | .922 | |||||||
| CART | 51.1 ± 1.1 | 51.9 ± 1.1 | 52.8 ± 1.2 | 52.5 ± 1.2 | 0.8 (−1.2 to 2.8) | 1.7 (−0.5 to 3.9) | 1.3 (−1.1 to 3.7) | ||
| SLOW | 52.1 ± 1.2 | 52.4 ± 1.1 | 53.7 ± 1.2 | 52.4 ± 1.3 | 0.3 (−1.8 to 2.4) | 1.6 (−0.7 to 3.9) | 0.3 (−2.2 to 2.8) | ||
| Differential change | … | … | … | … | 0.5 (−2.4 to 3.4) | 0.1 (−3.1 to 3.3) | 1.0 (−2.5 to 4.5) | ||
| P value | … | … | … | … | .740 | .959 | .564 | ||
| KASE-AQ | < .001 | .665 | |||||||
| CART | 53.9 ± 1.3 | 60.3 ± 1.3 | 60.6 ± 1.2 | 62.1 ± 1.3 | 6.5 (4.0 to 8.9) | 6.7 (4.3 to 9.0) | 8.3 (5.6 to 10.9) | ||
| SLOW | 52.5 ± 1.3 | 57.0 ± 1.3 | 58.0 ± 1.2 | 58.6 ± 1.3 | 4.5 (2.0 to 7.0) | 5.6 (3.2 to 7.9) | 6.2 (3.4 to 8.9) | ||
| Differential change | … | … | … | … | 2.0 (−1.5 to 5.5) | 1.1 (−2.2 to 4.5) | 2.1 (−1.8 to 6.0) | ||
| P value | … | … | … | … | .258 | .508 | .283 | ||
| Bronchodilator use | < .001 | .922 | |||||||
| CART | 1.4 ± 0.3 | 1.0 ± 0.3 | 0.5 ± 0.1 | 0.4 ± 0.1 | −0.4 (−1.0 to 0.3) | −0.9 (−1.5 to −0.3) | −1.0 (−1.6 to −0.4) | ||
| SLOW | 1.3 ± 0.4 | 0.8 ± 0.3 | 0.4 ± 0.1 | 0.3 ± 0.1 | −0.5 (−1.2 to 0.2) | −1.0 (−1.6 to −0.3) | −1.0 (−1.7 to −0.3) | ||
| Differential change | … | … | … | … | 0.1 (−0.8 to 1.1) | 0.1 (−0.8 to 1.0) | 0.0 (−0.9 to 0.9) | ||
| P value | … | … | … | … | .758 | .836 | .982 | ||
Differential change was calculated as the difference from baseline in the CART condition (eg, 1MFU − baseline) minus the difference from baseline for the SLOW condition; higher numbers indicate greater increases in CART vs SLOW. ASC = Asthma Symptom Checklist; ASQ = Asthma Symptom Questionnaire; KASE-AQ = Knowledge, Attitude, and Self-efficacy Asthma Questionnaire; SF-12 = Survey Form-12. See Table 1 and 2 legends for expansion of other abbreviations.