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. 1978 Jul;21(1):229–237. doi: 10.1128/iai.21.1.229-237.1978

Escherichia coli pili as possible mediators of attachment to human urinary tract epithelial cells.

C S Edén, H A Hansson
PMCID: PMC421981  PMID: 361565

Abstract

Presence of pili of fimbriae on Escherichia coli bacteria isolated from the urine of patients with urinary tract infection was related to the ability of the bacteria to attach to human uroepithelial cells. Piliated E. coli strains agglutinated guinea pig erythrocytes. D-Mannose and alpha-methyl-D-mannopyranoside inhibited this agglutination with all but one of the 12 strains tested. D-Mannose, D-galactose, alpha-methyl-D-mannopyranoside, and L-fucose did not afect attachment of piliated strains to uroepithelial cells. Heating as well as washing of piliated strains caused a parallel decrease of piliation and adhesive ability. Growth in glucose-enriched medium increased capsule formation but decreased piliation and adhesion. Capsulated strains retained their adhesive ability provided that pili extended outside the capsule.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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