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. 1978 Sep;21(3):989–993. doi: 10.1128/iai.21.3.989-993.1978

Cytotoxic activity of Aeromonas hydrophila.

S T Donta, A D Haddow
PMCID: PMC422094  PMID: 711344

Abstract

Most strains of Aeromonas hydrophila tested demonstrated cytotoxic activity on several tissue-cultured cell lines. The cytotoxin is heat-labile, non-dialyzable, and immunologically distinct from that of Shigella dysenteriae and Clostridium perfringens. None of the aeromonas isolates was found to be enterotoxigenic by either tissue culture or rabbit ileal loop assays.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Annapurna E., Sanyal S. C. Enterotoxicity of Aeromonas hydrophila. J Med Microbiol. 1977 Aug;10(3):317–323. doi: 10.1099/00222615-10-3-317. [DOI] [PubMed] [Google Scholar]
  2. Boulanger Y., Lallier R., Cousineau G. Isolation of enterotoxigenic Aeromonas from fish. Can J Microbiol. 1977 Sep;23(9):1161–1164. doi: 10.1139/m77-174. [DOI] [PubMed] [Google Scholar]
  3. Donta S. T. Alteration of tyrosine aminotransferase activity in hepatoma cells in tissue culture by amphotericin B. Antimicrob Agents Chemother. 1974 Mar;5(3):240–246. doi: 10.1128/aac.5.3.240. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Donta S. T., Moon H. W., Whipp S. C. Detection of heat-labile Escherichia coli enterotoxin with the use of adrenal cells in tissue culture. Science. 1974 Jan 25;183(4122):334–336. doi: 10.1126/science.183.4122.334. [DOI] [PubMed] [Google Scholar]
  5. Donta S. T., Moon H. W., Whipp S. C., Skartvedt S. M. In vitro production and inactivation of Escherichia coli enterotoxin. Gastroenterology. 1974 Nov;67(5):983–990. [PubMed] [Google Scholar]
  6. Donta S. T., Smith D. M. Stimulation of steroidogenesis in tissue culture by enterotoxigenic Escherichia coli and its neutralization by specific antiserum. Infect Immun. 1974 Mar;9(3):500–505. doi: 10.1128/iai.9.3.500-505.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Donta S. T. The growth of functional rat glial cells in a serumless medium. Exp Cell Res. 1973 Nov;82(1):119–124. doi: 10.1016/0014-4827(73)90252-8. [DOI] [PubMed] [Google Scholar]
  8. Guerrant R. L., Moore R. A., Kirschenfeld P. M., Sande M. A. Role of toxigenic and invasive bacteria in acute diarrhea of childhood. N Engl J Med. 1975 Sep 18;293(12):567–572. doi: 10.1056/NEJM197509182931201. [DOI] [PubMed] [Google Scholar]
  9. Ketover B. P., Young L. S., Armstrong D. Septicemia due to Aeromonas hydrophila: clinical and immunologic aspects. J Infect Dis. 1973 Mar;127(3):284–290. doi: 10.1093/infdis/127.3.284. [DOI] [PubMed] [Google Scholar]
  10. Keusch G. T., Donta S. T. Classification of enterotoxins on the basis of activity in cell culture. J Infect Dis. 1975 Jan;131(1):58–63. doi: 10.1093/infdis/131.1.58. [DOI] [PubMed] [Google Scholar]
  11. Klipstein F. A., Engert R. F. Immunological interrelationships between cholera toxin and the heat-labile and heat-stable enterotoxins of coliform bacteria. Infect Immun. 1977 Oct;18(1):110–117. doi: 10.1128/iai.18.1.110-117.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Klipstein F. A., Schenk E. A. Enterotoxigenic intestinal bacteria in tropical sprue. II. Effect of the bacteria and their enterotoxins on intestinal structure. Gastroenterology. 1975 Apr;68(4 Pt 1):642–655. [PubMed] [Google Scholar]
  13. Ljungh A., Popoff M., Wadstrom T. Aeromonas hydrophila in acute diarrheal disease: detection of enterotoxin and biotyping of strains. J Clin Microbiol. 1977 Aug;6(2):96–100. doi: 10.1128/jcm.6.2.96-100.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Pearson T. A., Mitchell C. A., Hughes W. T. Aeromonas hydrophila septicemia. Am J Dis Child. 1972 Jun;123(6):579–582. doi: 10.1001/archpedi.1972.02110120103012. [DOI] [PubMed] [Google Scholar]
  15. Qadri S. M., Gordon L. P., Wende R. D., Williams R. P. Meningitis due to Aeromonas hydrophila. J Clin Microbiol. 1976 Feb;3(2):102–104. doi: 10.1128/jcm.3.2.102-104.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Ramsay A. M., Rosenbaum B. J., Yarbrough C. L., Hotz J. A. Aeromonas hydrophila sepsis in a patient undergoing hemodialysis therapy. JAMA. 1978 Jan 9;239(2):128–129. [PubMed] [Google Scholar]
  17. Sanyal S. C., Singh S. J., Sen P. C. Enteropathogenicity of Aeromonas hydrophila and Plesiomonas shigelloides. J Med Microbiol. 1975 Feb;8(1):195–198. doi: 10.1099/00222615-8-1-195. [DOI] [PubMed] [Google Scholar]
  18. Shackelford P. G., Ratzan S. A., Shearer W. T. Ecthyma gangrenosum produced by Aeromonas hydrophilia. J Pediatr. 1973 Jul;83(1):100–101. doi: 10.1016/s0022-3476(73)80326-9. [DOI] [PubMed] [Google Scholar]
  19. Tapper M. L., McCarthy L. R., Mayo J. B., Armstrong D. Recurrent Aeromonas sepsis in a patient with leukemia. Am J Clin Pathol. 1975 Oct;64(4):525–530. doi: 10.1093/ajcp/64.4.525. [DOI] [PubMed] [Google Scholar]
  20. Wadström T., Aust-Kettis A., Habte D., Holmgren J., Meeuwisse G., Möllby R., Söderlind O. Enterotoxin-producing bacteria and parasites in stools of Ethiopian children with diarrhoeal disease. Arch Dis Child. 1976 Nov;51(11):865–870. doi: 10.1136/adc.51.11.865. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Wadström T., Ljungh A., Wretlind B. Enterotoxin, haemolysin and cytotoxic protein in Aeromonas hydrophila from human infections. Acta Pathol Microbiol Scand B. 1976 Apr;84(2):112–114. doi: 10.1111/j.1699-0463.1976.tb01911.x. [DOI] [PubMed] [Google Scholar]

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