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. 1978 Dec;22(3):786–789. doi: 10.1128/iai.22.3.786-789.1978

Interferon production in glia and glioma cell lines.

I Larsson, L E Landström, E Larner, E Lundgren, H Miörner, L Strannegård
PMCID: PMC422229  PMID: 730383

Abstract

Interferon (IF) was produced in glia and glioma cell lines in titers comparable to those produced by human fibroblasts. It was inducible by both Sendai virus and polyriboinosinic:polyribocytidylic acid. "Superinduction" resulted in up to 500-fold-higher titers of IF. The IF appeared to be of the fibroblast type, as revealed by experiments using heat treatment, assay of antiviral activity in heterologous cell lines, and neutralization with specific antisera. Since large amounts of IF may easily be produced with glioma cell lines, such cells may be suitable for mass production of IF.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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