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. 1978 Mar;19(3):908–911. doi: 10.1128/iai.19.3.908-911.1978

Production of enterotoxin by Yersinia enterocolitica.

C H Pai, V Mors
PMCID: PMC422276  PMID: 640737

Abstract

Forty-three strains of Yersinia enterocolitica isolated from children with gastroenteritis and 18 laboratory strains were examined for enterotoxin production by using the infant mouse, Y1 adrenal cell, and rabbit ileal loop assay systems. All clinical isolates and seven laboratory strains were found enterotoxigenic in the infant mouse model, but none of the strains produced toxin in the Y1 adrenal cell system. One enterotoxin-producing strain was also tested by the rabbit ileal loop assay, confirming the results of the infant mouse assay. The enterotoxin was heat-stable and as active in the 6-h rabbit ileal loop as in the 18-h assay, suggesting a similarity to the heat-stable enterotoxin of Escherichia coli.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bottone E. J., Robin T. Yersinia enterocolitica: recovery and characterization of two unusual isolates from a case of acute enteritis. J Clin Microbiol. 1977 Mar;5(3):341–345. doi: 10.1128/jcm.5.3.341-345.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Carter P. B., Collins F. M. Experimental Yersinia enterocolitica infection in mice: kinetics of growth. Infect Immun. 1974 May;9(5):851–857. doi: 10.1128/iai.9.5.851-857.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Carter P. B. Pathogenecity of Yersinia enterocolitica for mice. Infect Immun. 1975 Jan;11(1):164–170. doi: 10.1128/iai.11.1.164-170.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dean A. G., Ching Y. C., Williams R. G., Harden L. B. Test for Escherichia coli enterotoxin using infant mice: application in a study of diarrhea in children in Honolulu. J Infect Dis. 1972 Apr;125(4):407–411. doi: 10.1093/infdis/125.4.407. [DOI] [PubMed] [Google Scholar]
  5. Evans D. G., Evans D. J., Jr, Pierce N. F. Differences in the response of rabbit small intestine to heat-labile and heat-stable enterotoxins of Escherichia coli. Infect Immun. 1973 Jun;7(6):873–880. doi: 10.1128/iai.7.6.873-880.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Jepsen O. B., Korner B., Lauritsen K. B., Hancke A. B., Andersen L., Henrichsen S., Brenoe E., Christiansen P. M., Johansen A. Yersinia enterocolitica infection in patients with acute surgical abdominal disease. A prospective study. Scand J Infect Dis. 1976;8(3):189–194. doi: 10.3109/inf.1976.8.issue-3.13. [DOI] [PubMed] [Google Scholar]
  7. Morris G. K., Merson M. H., Sack D. A., Wells J. G., Martin W. T., Dewitt W. E., Feeley J. C., Sack R. B., Bessudo D. M. Laboratory investigation of diarrhea in travelers to Mexico: evaluation of methods for detecting enterotoxigenic Echerichia coli. J Clin Microbiol. 1976 May;3(5):486–495. doi: 10.1128/jcm.3.5.486-495.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Rabson A. R., Hallett A. F., Koornhof H. J. Generalized Yersinia enterocolitica infection. J Infect Dis. 1975 Apr;131(4):447–451. doi: 10.1093/infdis/131.4.447. [DOI] [PubMed] [Google Scholar]
  9. SERENY B. Experimental shigella keratoconjunctivitis; a preliminary report. Acta Microbiol Acad Sci Hung. 1955;2(3):293–296. [PubMed] [Google Scholar]
  10. Sack D. A., Merson M. H., Wells J. G., Sack R. B., Morris G. K. Diarrhoea associated with heat-stable enterotoxin-producing strains of Escherichia coli. Lancet. 1975 Aug 9;2(7928):239–241. doi: 10.1016/s0140-6736(75)90958-7. [DOI] [PubMed] [Google Scholar]
  11. Sack D. A., Sack R. B. Test for enterotoxigenic Escherichia coli using Y-1 adrenal cells in miniculture. Infect Immun. 1975 Feb;11(2):334–336. doi: 10.1128/iai.11.2.334-336.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Sebes J. I., Mabry E. H., Jr, Rabinowitz J. G. Lung abscess and osteomyelitis of rib due to Yersinia enterocolitica. Chest. 1976 Apr;69(4):546–548. doi: 10.1378/chest.69.4.546. [DOI] [PubMed] [Google Scholar]
  13. Spira T. J., Kabins S. A. Yersinia enterocolitica septicemia with septic arthritis. Arch Intern Med. 1976 Nov;136(11):1305–1308. [PubMed] [Google Scholar]
  14. Toma S., Lafleur L. Survey on the incidence of Yersinia enterocolitica infection in Canada. Appl Microbiol. 1974 Sep;28(3):469–473. doi: 10.1128/am.28.3.469-473.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Whipp S. C., Moon H. W., Lyon N. C. Heat-stable Escherichia coli enterotoxin production in vivo. Infect Immun. 1975 Aug;12(2):240–244. doi: 10.1128/iai.12.2.240-244.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Winblad S. Arthritis associated with Yersinia enterocolitica infections. Scand J Infect Dis. 1975;7(3):191–195. doi: 10.3109/inf.1975.7.issue-3.07. [DOI] [PubMed] [Google Scholar]

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