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. 1972 Jan;5(1):48–54. doi: 10.1128/iai.5.1.48-54.1972

Relationship of Serogroups of Neisseria meningitidis II. R Variants of Neisseria meningitidis

Leonard F Devine a, Solon L Rhode III a,1, Cline R Hagerman a
PMCID: PMC422319  PMID: 4632468

Abstract

Meningococci isolated in primary cultures from nasopharyngeal carriers occasionally consisted of mixtures of smooth (S) and rough (R) strains. The R strains were separated from the S strains and their morphological and serological characteristics were studied. Some of these R strains reverted spontaneously to S strains which subsequently produced group-specific polysaccharide. Several R strains, grown in the presence of deoxyribonucleic acid from either an R strain of known parentage or an S strain, formed recombinants with serological group specificity.

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Selected References

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